The NYU RNAi Core Facility provides an integrated, state-of-the-art, RNA interference (RNAi) based high-throughput screening (HTS) facility at the NYU Langone Medical Center. The facility is committed to offering siRNA/dsRNA screening libraries for the cross-species functional characterization of whole genomes in a systematic, comprehensive, and cost effective manner. In addition, the facility may also provide logistic, technical, and bioinformatic support in order to assist screeners in performing and interpreting their genome scale RNAi screens. Importantly, we are strongly committed to making the NYU RNAi Core Facility fully accessible to the entire academic community**, both at the national and international level, in order to facilitate inter-disciplinary and multi-institutional collaborations.
The facility offers the following siRNA/dsRNA libraries for HTS:
• Human annotated genome (siRNA library from Ambion)
• Human pre-miR and anti-miR miRNA collection (from Ambion)
• Mouse druggable genome (siRNA library from Ambion)
• Drosophila whole genome and functional group subsets (dsRNA libraries in collaboration with
DRSC, Harvard Medical School)**
• C. elegans whole genome (2 bacterial feeding libraries from Vidal and Ahringer collections)
** The Drosophila libraries are access-restricted to researchers in the New York-tri-state area; others are requested to contact DRSC, Harvard Medical School.
